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rhegfr fc  (R&D Systems)


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    R&D Systems rhegfr fc
    Rhegfr Fc, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 73 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rhegfr fc/product/R&D Systems
    Average 94 stars, based on 73 article reviews
    rhegfr fc - by Bioz Stars, 2026-03
    94/100 stars

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    Immunogenicity of EGFR peptide vaccine in outbred rabbits and antiproliferative effects in rabbit Abs and peptide mimics. (A–C) Relative levels of vaccine Abs measured in <t>an</t> <t>ELISA</t> assay showing immunogenicity of peptide constructs in rabbits (two per each construct). 2y + 3w, for example, indicates the titer of blood drawn 3 wk after the second immunization. (D) Binding of vaccine Abs to <t>rhEGFR.</t> y-axis represents absorbance, which shows levels of binding. MTT cell proliferation assay with breast and lung cancer cells using 50 μg/ml of vaccine Abs (E) and 50 μg/ml of peptide mimics (F) as inhibitors. The percentage inhibition was calculated using the formula (ODUNTREATED – ODTREATED)/ODUNTREATED × 100, and data shown represent an average of three different experiments, with error bars showing SD from the mean.
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    Immunogenicity of EGFR peptide vaccine in outbred rabbits and antiproliferative effects in rabbit Abs and peptide mimics. (A–C) Relative levels of vaccine Abs measured in <t>an</t> <t>ELISA</t> assay showing immunogenicity of peptide constructs in rabbits (two per each construct). 2y + 3w, for example, indicates the titer of blood drawn 3 wk after the second immunization. (D) Binding of vaccine Abs to <t>rhEGFR.</t> y-axis represents absorbance, which shows levels of binding. MTT cell proliferation assay with breast and lung cancer cells using 50 μg/ml of vaccine Abs (E) and 50 μg/ml of peptide mimics (F) as inhibitors. The percentage inhibition was calculated using the formula (ODUNTREATED – ODTREATED)/ODUNTREATED × 100, and data shown represent an average of three different experiments, with error bars showing SD from the mean.
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    Immunogenicity of EGFR peptide vaccine in outbred rabbits and antiproliferative effects in rabbit Abs and peptide mimics. (A–C) Relative levels of vaccine Abs measured in an ELISA assay showing immunogenicity of peptide constructs in rabbits (two per each construct). 2y + 3w, for example, indicates the titer of blood drawn 3 wk after the second immunization. (D) Binding of vaccine Abs to rhEGFR. y-axis represents absorbance, which shows levels of binding. MTT cell proliferation assay with breast and lung cancer cells using 50 μg/ml of vaccine Abs (E) and 50 μg/ml of peptide mimics (F) as inhibitors. The percentage inhibition was calculated using the formula (ODUNTREATED – ODTREATED)/ODUNTREATED × 100, and data shown represent an average of three different experiments, with error bars showing SD from the mean.

    Journal: Journal of immunology (Baltimore, Md. : 1950)

    Article Title: Peptide Vaccines and Peptidomimetics of EGFR (HER-1) Ligand Binding Domain Inhibit Cancer Cell Growth In Vitro and In Vivo

    doi: 10.4049/jimmunol.1300231

    Figure Lengend Snippet: Immunogenicity of EGFR peptide vaccine in outbred rabbits and antiproliferative effects in rabbit Abs and peptide mimics. (A–C) Relative levels of vaccine Abs measured in an ELISA assay showing immunogenicity of peptide constructs in rabbits (two per each construct). 2y + 3w, for example, indicates the titer of blood drawn 3 wk after the second immunization. (D) Binding of vaccine Abs to rhEGFR. y-axis represents absorbance, which shows levels of binding. MTT cell proliferation assay with breast and lung cancer cells using 50 μg/ml of vaccine Abs (E) and 50 μg/ml of peptide mimics (F) as inhibitors. The percentage inhibition was calculated using the formula (ODUNTREATED – ODTREATED)/ODUNTREATED × 100, and data shown represent an average of three different experiments, with error bars showing SD from the mean.

    Article Snippet: ELISA was performed to evaluate the binding of the vaccine Abs to rhEGFR (R&D Systems) (as described in Ref. 20 ).

    Techniques: Enzyme-linked Immunosorbent Assay, Construct, Binding Assay, MTT Cell Proliferation, Inhibition